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4TU5

Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1062)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1XDihydrofolate reductasepolymer15718015.61UniProt (Q2YY41)
Pfam (PF00186)
UniProt (by SIFTS) (A0A0M3KKX1)
In PDB
Staphylococcus aureus
2XNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
3X6-ethyl-5-{(3S)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diaminenon-polymer373.51Chemie (06W)
4waterwater18.0138Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18015.6
Non-Polymers*Number of molecules2
Total formula weight1118.9
All*Total formula weight19134.4
*Water molecules are not included.

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PDB entries from 2024-05-15

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