4TTI
Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 4 FMC molecules
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Purine nucleoside phosphorylase DeoD-type | polymer | 237 | 25591.5 | 6 | UniProt (P0ABP8) Pfam (PF01048) | Escherichia coli | PNP,Inosine phosphorylase |
| 2 | G, J, O, S (A, C, D, F) | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol | non-polymer | 267.2 | 4 | Chemie (FMC) | |||
| 3 | H, I, K, N, Q... (A, B, C, D, E...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 4 | L, M, P, R, U (C, D, E, F) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | AA, V, W, X, Y... (F, A, B, C, D...) | water | water | 18.0 | 1247 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 237 (UniProt: P0ABP8)
| PDB | External Database | Details |
|---|---|---|
| Ala 204 | Asp 205 | engineered mutation |
| Ala 217 | Arg 218 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 153549.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2119.1 | |
| All* | Total formula weight | 155668.2 |
