4TTA
Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 2 FMC molecules
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Purine nucleoside phosphorylase DeoD-type | polymer | 237 | 25591.5 | 6 | UniProt (U0SVH6) Pfam (PF01048) UniProt (by SIFTS) (P0ABP8) In PDB | Escherichia coli | PNP, Purine nucleoside phosphorylase wild type from E. coli |
| 2 | A, B, C, D, E... | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 3 | C, D | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol | non-polymer | 267.2 | 2 | Chemie (FMC) | |||
| 4 | C, D, E, F | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 1321 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 237 (UniProt: U0SVH6)
| PDB | External Database | Details |
|---|---|---|
| Ala 204 | Asp 205 | conflict |
| Ala 217 | Arg 218 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 153549.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1680.7 | |
| All* | Total formula weight | 155229.7 |
