4TSV
HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TUMOR NECROSIS FACTOR-ALPHA | polymer | 150 | 16578.8 | 1 | UniProt (P01375) Pfam (PF00229) | Homo sapiens (human) | |
| 2 | B (A) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 8 - 157 (UniProt: P01375)
| PDB | External Database | Details |
|---|---|---|
| Ser 29 | Leu 105 | engineered mutation |
| Ile 52 | Ser 128 | engineered mutation |
| Phe 56 | Tyr 132 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16578.8 | |
| All* | Total formula weight | 16578.8 |
