4TRZ
Structure of BACE1 complex with 2-thiophenyl HEA-type inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Beta-secretase 1 | polymer | 388 | 43281.8 | 3 | UniProt (P56817) Pfam (PF00026) | Homo sapiens (Human) | Aspartyl protease 2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2 |
| 2 | D, E, F (D, E, F) | 2-thiophenyl HEA-type inhibitor | polymer | 4 | 681.9 | 3 | BIRD (PRD_002107) | synthetic construct | |
| 3 | G, H, I, J (A, B, C, F) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 131891.1 | |
| All* | Total formula weight | 131891.1 |
