4TPG
Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proton:oligopeptide symporter POT family | polymer | 523 | 57224.2 | 2 | UniProt (Q8EHE6) Pfam (PF00854) | Shewanella oneidensis MR-1 | A secondary active peptide transporter in complex with a tripeptide AYA. |
| 2 | C (E) | Ala-L-3-Br-Tyr-Ala | polymer | 3 | 481.1 | 1 | BIRD (PRD_002092) | synthetic construct | |
| 3 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | E, F (A, B) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 2 | Chemie (LMT) |
Sequence modifications
A, B: 1 - 516 (UniProt: Q8EHE6)
| PDB | External Database | Details |
|---|---|---|
| Ala 517 | - | expression tag |
| Glu 518 | - | expression tag |
| Asn 519 | - | expression tag |
| Leu 520 | - | expression tag |
| Tyr 521 | - | expression tag |
| Phe 522 | - | expression tag |
| Gln 523 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 114929.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1086.6 | |
| All* | Total formula weight | 116016.1 |
