4TNS
Structure of Pin1 PPIase domain bound with all-trans retinoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | polymer | 151 | 16636.5 | 2 | UniProt (Q13526) Pfam (PF00639) | Homo sapiens (Human) | Peptidyl-prolyl cis-trans isomerase Pin1,PPIase Pin1,Rotamase Pin1 |
| 2 | C (A) | RETINOIC ACID | non-polymer | 300.4 | 1 | Chemie (REA) PubChem (5538) PubChem (23275881) PubChem (25145416) PubChem (444795) PubChem (449171) PubChem (5282379) PubChem (6336207) PubChem (6336229) PubChem (6419708) PubChem (87179195) PubChem (87519764) PubChem (87980058) PubChem (88439848) PubChem (88525859) PubChem (88604688) PubChem (6603983) PubChem (9796370) PubChem (9861147) PubChem (445925) PubChem (10881132) PubChem (12358677) PubChem (12358678) PubChem (12358679) PubChem (12358681) PubChem (134688661) PubChem (139597075) PubChem (145826768) PubChem (166478803) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 163 (UniProt: Q13526)
| PDB | External Database | Details |
|---|---|---|
| Met 13 | - | initiating methionine |
| Gly 14 | - | expression tag |
| Ser 15 | - | expression tag |
| Ser 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| His 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Leu 26 | - | expression tag |
| Val 27 | - | expression tag |
| Pro 28 | - | expression tag |
| Arg 29 | - | expression tag |
| Gly 30 | - | expression tag |
| Ser 31 | - | expression tag |
| His 32 | - | expression tag |
| Met 33 | - | expression tag |
| Leu 34 | - | expression tag |
| Glu 35 | - | expression tag |
| Val 36 | - | expression tag |
| Leu 37 | - | expression tag |
| Phe 38 | - | expression tag |
| Gln 39 | - | expression tag |
| Gly 40 | - | expression tag |
| Pro 41 | - | expression tag |
| Gly 42 | - | expression tag |
| Gln 77 | Lys 77 | engineered mutation |
| Gln 82 | Lys 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33273.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 300.4 | |
| All* | Total formula weight | 33573.4 |
