4TNE
Crystal Structure of Human Transthyretin Thr119Tyr Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 125 | 13981.6 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (Human) | ATTR,Prealbumin,TBPA |
| 2 | C (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Tyr 119 | Thr 139 | engineered mutation |
| His 128 | - | expression tag |
| His 129 | - | expression tag |
| His 130 | - | expression tag |
| His 131 | - | expression tag |
| His 132 | - | expression tag |
| His 133 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27963.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 28055.4 |
