4TN6

CK1d in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Casein kinase I isoform delta	polymer	318	36663.2	2	UniProt (P48730) Pfam (PF00069)	Homo sapiens (Human)	CKId,Tau-protein kinase CSNK1D
2	C (A)	4-{4-(4-fluorophenyl)-1-[1-(1,2-oxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidin-2-amine	non-polymer		419.5	1	Chemie (PFO)
3	D, E, F, G, H... (A, B)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
4	K, L (A, B)	water	water		18.0	211	Chemie (HOH)

Sequence modifications

A, B: 1 - 301 (UniProt: P48730)

PDB	External Database	Details
Leu 302	-	expression tag
Val 303	-	expression tag
Pro 304	-	expression tag
Arg 305	-	expression tag
Gly 306	-	expression tag
Ser 307	-	expression tag
Pro 308	-	expression tag
Gly 309	-	expression tag
Gly 310	-	expression tag
Gly 311	-	expression tag
Ser 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73326.4
Non-Polymers*	Number of molecules	8
	Total formula weight	1091.9
All*	Total formula weight	74418.3

*Water molecules are not included.