4S2T

Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (P, Q)	Protein APP-1	polymer	639	72213.7	2	UniProt (O44750) Pfam (PF01321) Pfam (PF16189) Pfam (PF00557) Pfam (PF16188)	Caenorhabditis elegans (roundworm)
2	C, D (A, B)	apstatin	polymer	5	458.5	2	BIRD (PRD_000553)
3	E, F, J, K (P, Q)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	G, H, I, L, M... (P, Q)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
5	P, Q, R, S (P, Q, A, B)	water	water		18.0	352	Chemie (HOH)

Sequence modifications

P, Q: 1 - 616 (UniProt: O44750)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
His -7	-	expression tag
Ile -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	145344.5
Non-Polymers*	Number of molecules	11
	Total formula weight	934.1
All*	Total formula weight	146278.6

*Water molecules are not included.