4S2R

Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (P, Q)	Protein APP-1	polymer	639	72213.7	2	UniProt (O44750) Pfam (PF01321) Pfam (PF16189) Pfam (PF00557) Pfam (PF16188)	Caenorhabditis elegans (roundworm)
2	C, D, E, F (P, Q)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	G, H (P, Q)	water	water		18.0	596	Chemie (HOH)

Sequence modifications

P, Q: 1 - 616 (UniProt: O44750)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
His -7	-	expression tag
Ile -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	144427.4
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	144689.1

*Water molecules are not included.