4S1G

Renin in complex with (S)-1-(3-fluoro-5-(((S)-1-phenylethyl)carbamoyl)benzyl)-4-isopropyl-4-methyl-6-oxotetrahydropyrimidin-2(1H)-iminium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Renin	polymer	340	37267.0	2	UniProt (P00797) Pfam (PF00026)	Homo sapiens (human)	Angiotensinogenase
2	C, E (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D, F (A, B)	3-{[(4S)-2-amino-4-methyl-6-oxo-4-(propan-2-yl)-5,6-dihydropyrimidin-1(4H)-yl]methyl}-5-fluoro-N-[(1S)-1-phenylethyl]benzamide	non-polymer		424.5	2	Chemie (43T)
4	G, H (A, B)	water	water		18.0	294	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74534.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1291.4
All*	Total formula weight	75825.5

*Water molecules are not included.