4S14
Crystal structure of the orphan nuclear receptor RORgamma ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor ROR-gamma | polymer | 259 | 29913.5 | 1 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RAR-related orphan receptor C, Retinoid-related orphan receptor-gamma |
| 2 | B (C) | Nuclear receptor-interacting protein 1 | polymer | 12 | 1380.6 | 1 | UniProt (P48552) | Homo sapiens | Nuclear factor RIP140, Receptor-interacting protein 140 |
| 3 | C (A) | (3beta,4alpha,5beta,14beta)-3-hydroxy-4-methylcholesta-8,24-diene-4-carboxylic acid | non-polymer | 442.7 | 1 | Chemie (4D8) |
Sequence modifications
A: 262 - 518 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 260 | - | expression tag |
| Ser 261 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31294.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 442.7 | |
| All* | Total formula weight | 31736.8 |
