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4RY6

C-terminal mutant (W550A) of HCV/J4 RNA polymerase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
HCV J4 RNA polymerase (NS5B)polymer57063341.62UniProt (O92972)
Pfam (PF00998)
Hepatitis C virus isolate HC-J4 (HCV)RNA-dependent RNA polymerase
2C, D
(A, B)
waterwater18.0449Chemie (HOH)
Sequence modifications
A, B: 1 - 570 (UniProt: O92972)
PDBExternal DatabaseDetails
Ala 550Trp 2969engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight126683.2
All*Total formula weight126683.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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