4RWT

Structure of actin-Lmod complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, B)	Actin-5C	polymer	384	42886.8	2	UniProt (P10987) Pfam (PF00022)	Drosophila melanogaster (Fruit fly)
2	B, C (C, D)	Leiomodin-2	polymer	506	56753.7	2	UniProt (Q6P5Q4) Pfam (PF03250)	Homo sapiens (human)	Cardiac leiomodin, C-LMOD
3	E, G (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
4	F, H (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

A, B: 0 - 375 (UniProt: P10987)

PDB	External Database	Details
Glu 291	Lys 292	engineered mutation
Lys 322	Pro 323	engineered mutation
Ala 376	-	expression tag
Ser 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag

C, D: 1 - 495 (UniProt: Q6P5Q4)

PDB	External Database	Details
Met -10	-	expression tag
Ala -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Val -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag
-	Glu 97	deletion
-	Glu 98	deletion
-	Ser 99	deletion
-	Glu 100	deletion
-	Glu 101	deletion
-	Glu 102	deletion
-	Leu 103	deletion
-	Ile 104	deletion
-	Phe 105	deletion
-	Thr 106	deletion
-	Glu 107	deletion
-	Ser 108	deletion
-	Asn 109	deletion
-	Ser 110	deletion
-	Glu 111	deletion
-	Val 112	deletion
-	Ser 113	deletion
-	Glu 114	deletion
-	Glu 115	deletion
-	Val 116	deletion
-	Tyr 117	deletion
-	Thr 118	deletion
-	Glu 119	deletion
-	Glu 120	deletion
-	Glu 121	deletion
-	Glu 122	deletion
-	Glu 123	deletion
-	Glu 124	deletion
-	Ser 125	deletion
-	Gln 126	deletion
-	Glu 127	deletion
-	Glu 128	deletion
-	Pro 421	deletion
-	Pro 422	deletion
-	Pro 423	deletion
-	Pro 424	deletion
-	Pro 425	deletion
-	Pro 426	deletion
-	Pro 427	deletion
-	Pro 428	deletion
-	Pro 429	deletion
-	Pro 430	deletion
-	Pro 431	deletion
-	Pro 432	deletion
-	Pro 433	deletion
-	Ser 434	deletion
-	Ser 435	deletion
-	Gln 436	deletion
-	Arg 437	deletion
-	Leu 438	deletion
-	Pro 439	deletion
-	Pro 440	deletion
Gly 426	Lys 478	engineered mutation
Ser 427	Lys 479	engineered mutation
Gly 428	Lys 480	engineered mutation
Ser 429	Lys 481	engineered mutation
Gly 431	Lys 483	engineered mutation
Ser 432	Lys 484	engineered mutation
Gly 434	Lys 486	engineered mutation
Ser 435	Lys 487	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	199281.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1061.0
All*	Total formula weight	200342.0

*Water molecules are not included.