4RUL
Crystal structure of full-length E.Coli topoisomerase I in complex with ssDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA topoisomerase 1 | polymer | 867 | 97635.0 | 1 | UniProt (C9QXS7) Pfam (PF01751) Pfam (PF01131) Pfam (PF01396) Pfam (PF21372) Pfam (PF08272) UniProt (by SIFTS) (P06612) | Escherichia coli DH1 | DNA topoisomerase I |
| 2 | B (B) | single strand DNA | polymer | 29 | 8997.8 | 1 | synthetic construct | ||
| 3 | C, D, E, F (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | G, H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | K (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A: 2 - 865 (UniProt: C9QXS7)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 106632.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 738.0 | |
| All* | Total formula weight | 107370.8 |
