4RUH

Crystal structure of Human Carnosinase-2 (CN2) in complex with inhibitor, Bestatin at 2.25 A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cytosolic non-specific dipeptidase	polymer	475	52946.3	2	UniProt (Q96KP4) Pfam (PF01546) Pfam (PF07687)	Homo sapiens (human)	CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A
2	C, F (A, B)	2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID	non-polymer		308.4	2	Chemie (BES)
3	D, E, G, H (A, B)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
4	I, J (B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	K, L (A, B)	water	water		18.0	228	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	105892.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1020.7
All*	Total formula weight	106913.3

*Water molecules are not included.