4RU9
Crystal structure of human DNA polymerase eta inserting dCMPNPP opposite a MeFapy-dG adducted DNA template
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 432 | 48325.4 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (human) | RAD30 homolog A, Xeroderma pigmentosum variant type protein |
| 2 | B (T) | Nucleic acids Template: CAT(MF7)ATGACGCT | polymer | 12 | 3694.4 | 1 | synthetic construct | ||
| 3 | C (P) | Nucleic acids Primar: AGCGTCAT | polymer | 8 | 2426.6 | 1 | synthetic construct | ||
| 4 | D (A) | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine | non-polymer | 466.2 | 1 | Chemie (0KX) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G, H, I (A, T, P) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54446.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 514.8 | |
| All* | Total formula weight | 54961.2 |
