4RTV
Crystal structure of the Src tyrosine kinase SH3 domain S94A/Q128R mutant in complex with the high affinity synthetic peptide APP12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 61 | 6918.6 | 1 | UniProt (P00523) Pfam (PF00018) | Gallus gallus (bantam chickens) | Proto-oncogene c-Src, pp60c-src, p60-Src |
| 2 | B (B) | APP12 peptide | polymer | 13 | 1412.7 | 1 | |||
| 3 | C, D (A, B) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 85 - 141 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 81 | - | expression tag |
| Ser 82 | - | expression tag |
| His 83 | - | expression tag |
| Met 84 | - | expression tag |
| Ala 94 | Ser 94 | engineered mutation |
| Arg 128 | Gln 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 8331.3 | |
| All* | Total formula weight | 8331.3 |
