4RTU
Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T96G/Q128R mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Proto-oncogene tyrosine-protein kinase Src | polymer | 61 | 6890.5 | 1 | UniProt (P00523) Pfam (PF00018) In PDB | Gallus gallus (bantam chickens) | Proto-oncogene c-Src, pp60c-src, p60-Src |
| 2 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 3 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 85 - 141 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 81 | - | expression tag |
| Ser 82 | - | expression tag |
| His 83 | - | expression tag |
| Met 84 | - | expression tag |
| Gly 96 | Thr 96 | engineered mutation |
| Arg 128 | Gln 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6890.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 704.7 | |
| All* | Total formula weight | 7595.2 |
