4RPM

Crystal structure of the SAT domain from the non-reducing fungal polyketide synthase CazM with bound hexanoyl

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SAT domain from CazM	polymer	406	44576.1	1	UniProt (Q2GWK9) Pfam (PF16073)	Chaetomium globosum (Soil fungus)
2	B (A)	HEXANOIC ACID	non-polymer		116.2	1	Chemie (6NA)
3	C (A)	HEXANOYL-COENZYME A	non-polymer		865.7	1	Chemie (HXC)
4	D (A)	water	water		18.0	185	Chemie (HOH)

Sequence modifications

A: 2 - 398 (UniProt: Q2GWK9)

PDB	External Database	Details
Gly -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Mse 1	-	expression tag
Val 109	-	SEE REMARK 999
Leu 110	-	SEE REMARK 999
Ile 111	-	SEE REMARK 999
Gln 112	-	SEE REMARK 999
Leu 113	Arg 109	SEE REMARK 999
-	Arg 111	SEE REMARK 999
-	Arg 112	SEE REMARK 999
Gln 115	Thr 113	SEE REMARK 999
Trp 117	Lys 115	SEE REMARK 999
Tyr 119	Thr 117	SEE REMARK 999
Leu 120	Trp 118	SEE REMARK 999
Glu 121	Ser 119	SEE REMARK 999
Leu 122	Pro 120	SEE REMARK 999
Thr 123	Ala 121	SEE REMARK 999
Asp 126	-	SEE REMARK 999
His 127	-	SEE REMARK 999
Leu 128	-	SEE REMARK 999
Glu 129	-	SEE REMARK 999
Asp 130	-	SEE REMARK 999
Ala 132	-	SEE REMARK 999
Asp 133	-	SEE REMARK 999
Leu 134	-	SEE REMARK 999
Gln 135	-	SEE REMARK 999
Ala 136	-	SEE REMARK 999
Asp 137	-	SEE REMARK 999
Val 138	-	SEE REMARK 999
Val 139	-	SEE REMARK 999
Thr 140	-	SEE REMARK 999
Gln 142	-	SEE REMARK 999
Thr 143	-	SEE REMARK 999
Gln 144	-	SEE REMARK 999
Pro 145	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44576.1
Non-Polymers*	Number of molecules	2
	Total formula weight	981.8
All*	Total formula weight	45557.9

*Water molecules are not included.