4RMI
Human Sirt2 in complex with SirReal1 and Ac-Lys-OTC peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-dependent protein deacetylase sirtuin-2 | polymer | 304 | 34416.7 | 1 | UniProt (Q8IXJ6) Pfam (PF02146) | Homo sapiens (human) | Regulatory protein SIR2 homolog 2, SIR2-like protein 2 |
| 2 | B (B) | Ac-Lys-OTC peptide | polymer | 3 | 474.5 | 1 | synthetic construct | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | N-(5-benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide | non-polymer | 370.5 | 1 | Chemie (3TK) | |||
| 5 | E (A) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A: 56 - 356 (UniProt: Q8IXJ6)
| PDB | External Database | Details |
|---|---|---|
| Gly 53 | - | expression tag |
| His 54 | - | expression tag |
| Met 55 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34891.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 435.9 | |
| All* | Total formula weight | 35327.2 |
