4RME
Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB111 and coactivator peptide GRIP-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor RXR-alpha | polymer | 235 | 26395.6 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) | Homo sapiens | NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2 |
| 3 | C (A) | (2E,4E,6Z,8E)-3,7-dimethyl-8-[2-(3-methylbutyl)-3-(propan-2-yl)cyclohex-2-en-1-ylidene]octa-2,4,6-trienoic acid | non-polymer | 356.5 | 1 | Chemie (3T2) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27975.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 356.5 | |
| All* | Total formula weight | 28332.0 |
