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4RMD

Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with 9cUAB110 and coactivator peptide GRIP-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Retinoic acid receptor RXR-alphapolymer23526395.61UniProt (P19793)
Pfam (PF00104)
Homo sapiens (human)Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha
2B
(B)
Nuclear receptor coactivator 2polymer131579.91UniProt (Q15596)Homo sapiensNCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3C
(A)
(2E,4E,6Z,8E)-8-[3-cyclopropyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethylocta-2,4,6-trienoic acidnon-polymer354.51Chemie (3SW)
4D, E
(A, B)
waterwater18.0124Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27975.5
Non-Polymers*Number of molecules1
Total formula weight354.5
All*Total formula weight28330.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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