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4RMC

Crystal Structure of human retinoid X receptor alpha-ligand binding domain complex with 9cUAB76 and the coactivator peptide GRIP-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Retinoic acid receptor RXR-alphapolymer23125897.01UniProt (P19793)
Pfam (PF00104)
Homo sapiens (human)Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha
2B
(B)
Nuclear receptor coactivator 2polymer131579.91UniProt (Q15596)Homo sapiensNCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3C
(A)
(3S,7S,8E)-8-[3-ethyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethyloctanoic acidnon-polymer348.61Chemie (3SV)
4D, E
(A, B)
waterwater18.0130Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27476.9
Non-Polymers*Number of molecules1
Total formula weight348.6
All*Total formula weight27825.5
*Water molecules are not included.

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PDB entries from 2025-07-30

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