4RLO
Human p70s6k1 with ruthenium-based inhibitor EM5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Ribosomal protein S6 kinase beta-1 | polymer | 288 | 32691.3 | 2 | UniProt (P23443) Pfam (PF00069) In PDB | Homo sapiens (human) | S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA |
| 2 | A | [(amino-kappaN)methanethiolato](3-fluoro-9-hydroxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium | non-polymer | 662.8 | 1 | Chemie (3T3) | |||
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 5 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | B | STAUROSPORINE | non-polymer | 466.5 | 1 | Chemie (STU) | |||
| 7 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 8 | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65382.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1888.6 | |
| All* | Total formula weight | 67271.2 |
