4RL0

Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase NDM-1	polymer	242	25631.8	2	UniProt (C7C422) Pfam (PF00753)	Klebsiella pneumoniae	NDM-1, Metallo-beta-lactamase NDM-1
2	C, D, F, G (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	E, H (A, B)	(2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid	non-polymer		442.4	2	Chemie (3S0)
4	I, J (A, B)	water	water		18.0	645	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51263.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1146.4
All*	Total formula weight	52410.1

*Water molecules are not included.