4RIC

FAN1 Nuclease bound to 5' hydroxyl (dT-dT) single flap DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Fanconi-associated nuclease 1	polymer	631	71983.9	2	UniProt (Q9Y2M0) Pfam (PF21315) Pfam (PF21169) Pfam (PF21170) Pfam (PF08774) In PDB	Homo sapiens (human)	FANCD2/FANCI-associated nuclease 1, Myotubularin-related protein 15
2	X, U	DNA (5'-D(*TP*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*TP*AP*GP*AP*CP*TP*CP*CP*TP*C)-3')	polymer	21	6319.1	2
3	Y, V	DNA (5'-D(*GP*CP*TP*GP*AP*GP*GP*AP*GP*TP*CP*T)-3')	polymer	12	3718.4	2
4	W, T	DNA (5'-D(*TP*TP*TP*TP*TP*TP*GP*AP*GP*GP*CP*GP*TP*G)-3')	polymer	14	4332.8	2
5	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)

Sequence modifications

A, B: 370 - 1009 (UniProt: Q9Y2M0)

PDB	External Database	Details
-	Cys 510	deletion
-	Thr 511	deletion
-	Trp 512	deletion
-	Gly 513	deletion
-	Lys 514	deletion
-	Asn 515	deletion
-	Lys 516	deletion
-	Pro 517	deletion
-	Gly 518	deletion

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	172708.5
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	172788.6

*Water molecules are not included.