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4RHT

Crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Hypoxanthine-guanine phosphoribosyltransferase Hptpolymer20122140.94UniProt (I6YCM5)
Pfam (PF00156)
UniProt (by SIFTS) (P9WHQ9)
Mycobacterium tuberculosis
2E, I, M, Q
(A, B, C, D)
PYROPHOSPHATE 2-non-polymer176.04Chemie (POP)
3F, J, N, R
(A, B, C, D)
GUANOSINE-5'-MONOPHOSPHATEnon-polymer363.24Chemie (5GP)
4G, H, K, L, O...
(A, B, C, D)
MAGNESIUM IONnon-polymer24.38Chemie (MG)
5U, V, W, X
(A, B, C, D)
waterwater18.044Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight88563.7
Non-Polymers*Number of molecules16
Total formula weight2351.2
All*Total formula weight90914.8
*Water molecules are not included.

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PDB entries from 2026-03-11

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