4RH7

Crystal structure of human cytoplasmic dynein 2 motor domain in complex with ADP.Vi

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Green fluorescent protein/Cytoplasmic dynein 2 heavy chain 1	polymer	3450	392963.1	1	UniProt (Q8NCM8) Pfam (PF08393) Pfam (PF18198) Pfam (PF18199) Pfam (PF12774) Pfam (PF21264) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028)	synthetic construct (artificial gene human)
2	B (A)	ADP ORTHOVANADATE	non-polymer		544.2	1	Chemie (AOV)
3	C, E (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	D (A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
5	F, G (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)

Sequence modifications

A: 859 - 1088 (PDB: 4RH7)
A: 1091 - 4307 (UniProt: Q8NCM8)

PDB	External Database	Details
Gly 1089	-	linker
Ser 1090	-	linker
Arg 1413	Lys 1413	variant
Gln 2871	Arg 2871	variant
Val 3680	Ala 3680	variant
Val 4308	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	392963.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1954.3
All*	Total formula weight	394917.4

*Water molecules are not included.