4RFO
Crystal structure of the ADCC-Potent Antibody N60-I3 Fab in complex with HIV-1 Clade A/E gp120 and M48u1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | HIV-1 clade A/E gp120 | polymer | 353 | 39160.4 | 1 | Pfam (PF00516) UniProt (by SIFTS) (Q0ED31) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | B (N) | m48u1 CD4 mimetic peptide | polymer | 28 | 3056.8 | 1 | BIRD (PRD_001094) | synthetic construct | |
| 3 | C (H) | N60-i3 Fab heavy chain | polymer | 229 | 24412.4 | 1 | Homo sapiens (human) | ||
| 4 | D (L) | N60-i3 Fab light chain | polymer | 221 | 23342.7 | 1 | Homo sapiens (human) | ||
| 5 | E, F, G, H, I... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 6 | N (H) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89972.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 91963.1 |
