4REA
A Nuclease DNA complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Fanconi-associated nuclease 1 | polymer | 647 | 73653.9 | 2 | UniProt (Q9Y2M0) Pfam (PF21315) Pfam (PF21169) Pfam (PF21170) Pfam (PF08774) In PDB | Homo sapiens (human) | FANCD2/FANCI-associated nuclease 1, Myotubularin-related protein 15 |
| 2 | C | DNA (5'-D(*TP*GP*CP*TP*CP*GP*CP*CP*AP*C)-3') | polymer | 10 | 2981.0 | 1 | synthetic construct | ||
| 3 | D | DNA (5'-D(P*CP*GP*TP*GP*GP*CP*GP*AP*GP*C)-3') | polymer | 10 | 3086.0 | 1 | synthetic construct | ||
| 4 | E | DNA (5'-D(P*GP*GP*CP*GP*AP*GP*CP*GP*CP*TP*CP*GP*CP*CP*AP*CP*G)-3') | polymer | 17 | 5214.4 | 1 | synthetic construct |
Sequence modifications
B, A: 373 - 1017 (UniProt: Q9Y2M0)
| PDB | External Database | Details |
|---|---|---|
| Glu 371 | - | expression tag |
| Phe 372 | - | expression tag |
| Ala 960 | Asp 960 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 158589.1 | |
| All* | Total formula weight | 158589.1 |
