4RCV

M. tuberculosis 1-deoxy-d-xylulose-5-phosphate reductoisomerase bound to 1-deoxy-L-erythrulose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	1-deoxy-D-xylulose 5-phosphate reductoisomerase	polymer	404	42466.9	2	UniProt (I6YAH0) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288) UniProt (by SIFTS) (P9WNS1)	Mycobacterium tuberculosis H37Rv	DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase
2	C, G (A, B)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	D, H (A, B)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
4	E (A)	1-deoxy-L-erythrulose	non-polymer		104.1	1	Chemie (DE2)
5	F, I (A, B)	PHOSPHITE ION	non-polymer		79.0	2	Chemie (PO3)
6	J, K (A, B)	water	water		18.0	133	Chemie (HOH)

Sequence modifications

A, B: 1 - 389 (UniProt: I6YAH0)

PDB	External Database	Details
Met -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Arg -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84933.8
Non-Polymers*	Number of molecules	7
	Total formula weight	1862.8
All*	Total formula weight	86796.6

*Water molecules are not included.