4RAW
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Ampicillin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Beta-lactamase NDM-1 | polymer | 243 | 25685.8 | 2 | UniProt (C7C422) Pfam (PF00753) In PDB | Klebsiella pneumoniae | NDM-1, Metallo-beta-lactamase NDM-1 |
2 | A, B | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | non-polymer | 367.4 | 2 | Chemie (ZZ7) | |||
3 | A, B | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | water | water | 18.0 | 373 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 270 (UniProt: C7C422)
PDB | External Database | Details |
---|---|---|
Ser 28 | - | expression tag |
Asn 29 | - | expression tag |
Ala 30 | - | expression tag |
Val 67 | Met 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 51371.7 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1246.6 | |
All* | Total formula weight | 52618.3 |