4RAW
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Ampicillin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase NDM-1 | polymer | 243 | 25685.8 | 2 | UniProt (C7C422) | Klebsiella pneumoniae | NDM-1, Metallo-beta-lactamase NDM-1 |
| 2 | C, G (A, B) | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | non-polymer | 367.4 | 2 | Chemie (ZZ7) PubChem (53364402) PubChem (76967799) PubChem (76967800) PubChem (6453491) PubChem (6914605) PubChem (11726464) PubChem (100971667) PubChem (100971666) PubChem (101043514) PubChem (101505298) PubChem (101543018) PubChem (131698399) PubChem (145865052) PubChem (163410307) | |||
| 3 | D, E, H, I (A, B) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) PubChem (31193) | |||
| 4 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 373 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Val 67 | Met 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51371.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1246.6 | |
| All* | Total formula weight | 52618.3 |
