4RAM
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Penicillin G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase NDM-1 | polymer | 243 | 25685.8 | 2 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | NDM-1, Metallo-beta-lactamase NDM-1 |
| 2 | C, D, E, H, I... (A, B) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 3 | F, K (A, B) | OPEN FORM - PENICILLIN G | non-polymer | 336.4 | 2 | Chemie (PNM) | |||
| 4 | G, M (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Val 67 | Met 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51371.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1201.6 | |
| All* | Total formula weight | 52573.3 |
