4R8L

Crystal structure of the Asp-bound guinea pig L-asparaginase 1 catalytic domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Uncharacterized protein	polymer	385	41977.4	4	UniProt (H0W0T5) Pfam (PF00710) Pfam (PF17763)	Cavia porcellus (guinea pig)	L-Asparaginase 1
2	E, F, G, H (A, B, C, D)	ASPARTIC ACID	non-polymer		133.1	4	Chemie (ASP)
3	I, J, K, L (A, B, C, D)	water	water		18.0	210	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 362 (UniProt: H0W0T5)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Asn -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	167909.7
Non-Polymers*	Number of molecules	4
	Total formula weight	532.4
All*	Total formula weight	168442.1

*Water molecules are not included.