4R7L
Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Leukotriene A-4 hydrolase | polymer | 631 | 71535.3 | 1 | UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) In PDB | Homo sapiens (human) | LTA-4 hydrolase, Leukotriene A(4) hydrolase |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | YTTERBIUM (III) ION | non-polymer | 173.0 | 1 | Chemie (YB) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 7 | A | OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE | non-polymer | 264.3 | 1 | Chemie (SHH) | |||
| 8 | water | water | 18.0 | 426 | Chemie (HOH) |
Sequence modifications
A: 0 - 610 (UniProt: P09960)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 71535.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 966.2 | |
| All* | Total formula weight | 72501.6 |
