4R3U
Crystal structure of 2-Hydroxyisobutyryl-CoA Mutase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2-hydroxyisobutyryl-CoA mutase large subunit | polymer | 584 | 66007.8 | 2 | UniProt (I3VE77) | Aquincola tertiaricarbonis | |
| 2 | C, D (C, D) | 2-hydroxyisobutyryl-CoA mutase small subunit | polymer | 158 | 17052.6 | 2 | UniProt (I3VE74) | Aquincola tertiaricarbonis | |
| 3 | E, H (A, B) | 3-HYDROXYBUTANOYL-COENZYME A | non-polymer | 853.6 | 2 | Chemie (3HC) PubChem (58332770) PubChem (46936728) PubChem (87657566) PubChem (521) PubChem (439419) PubChem (440563) PubChem (440045) PubChem (644065) PubChem (87071512) PubChem (87657569) PubChem (9543037) PubChem (124930685) PubChem (124930687) PubChem (133655802) PubChem (11966146) PubChem (124930686) PubChem (124930688) PubChem (175018497) PubChem (135071022) PubChem (170836232) | |||
| 4 | F, I (A, B) | S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} 2-hydroxy-2-methylpropanethioate | non-polymer | 853.6 | 2 | Chemie (3KK) PubChem (58332768) PubChem (87068711) PubChem (177669152) PubChem (174587824) | |||
| 5 | G (A) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 1 | Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (23638944) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (71678) PubChem (23615209) PubChem (40467849) PubChem (57115448) PubChem (439182) PubChem (59731278) PubChem (449044) PubChem (1277776) PubChem (90321697) PubChem (676784) PubChem (6541038) PubChem (6398669) PubChem (6928544) PubChem (121275112) PubChem (124363198) PubChem (12827542) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934) | |||
| 6 | J, K (C, D) | COBALAMIN | non-polymer | 1330.4 | 2 | Chemie (B12) | |||
| 7 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 562 (UniProt: I3VE77)
C, D: 1 - 136 (UniProt: I3VE74)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 563 | - | expression tag |
| Ser 564 | - | expression tag |
| Ala 565 | - | expression tag |
| Trp 566 | - | expression tag |
| Ser 567 | - | expression tag |
| His 568 | - | expression tag |
| Pro 569 | - | expression tag |
| Gln 570 | - | expression tag |
| Phe 571 | - | expression tag |
| Glu 572 | - | expression tag |
| Lys 573 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 137 | - | expression tag |
| Ser 138 | - | expression tag |
| Ala 139 | - | expression tag |
| Trp 140 | - | expression tag |
| Ser 141 | - | expression tag |
| His 142 | - | expression tag |
| Pro 143 | - | expression tag |
| Gln 144 | - | expression tag |
| Phe 145 | - | expression tag |
| Glu 146 | - | expression tag |
| Lys 147 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166120.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 6326.4 | |
| All* | Total formula weight | 172447.1 |
