4R3P
Crystal structures of EGFR in complex with Mig6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 323 | 36937.7 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
| 2 | B (B) | peptide from ERBB receptor feedback inhibitor 1 | polymer | 7 | 987.0 | 1 | UniProt (Q9UJM3) | Homo sapiens | Mitogen-inducible gene 6 protein, MIG-6 |
| 3 | C, D (A, B) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A: 696 - 1018 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Arg 858 | Leu 858 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37924.8 | |
| All* | Total formula weight | 37924.8 |
