4R2N

Crystal structure of Rv3772 in complex with its substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Putative phenylalanine aminotransferase	polymer	367	39704.2	4	UniProt (I6Y4H4) Pfam (PF00155) UniProt (by SIFTS) (P9WML5)	Mycobacterium tuberculosis H37Rv
2	E, H, K, N (A, B, C, D)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	4	Chemie (PLP)
3	F, I, L, O (A, B, C, D)	PHENYLALANINE	non-polymer		165.2	4	Chemie (PHE)
4	G, J, M, P (A, B, C, D)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	4	Chemie (EPE)
5	Q, R, S, T (A, B, C, D)	water	water		18.0	908	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 353 (UniProt: I6Y4H4)

PDB	External Database	Details
Met 0	-	expression tag
Val 1	-	expression tag
Lys 354	-	expression tag
Leu 355	-	expression tag
Ala 356	-	expression tag
Ala 357	-	expression tag
Ala 358	-	expression tag
Leu 359	-	expression tag
Glu 360	-	expression tag
His 361	-	expression tag
His 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	158816.9
Non-Polymers*	Number of molecules	12
	Total formula weight	2602.5
All*	Total formula weight	161419.5

*Water molecules are not included.