4QZF
Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-A base pair
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA nucleotidylexotransferase | polymer | 400 | 45627.9 | 1 | UniProt (P09838) Pfam (PF14716) Pfam (PF10391) Pfam (PF01909) Pfam (PF14791) In PDB | Mus musculus (mouse) | Terminal addition enzyme, Terminal deoxynucleotidyltransferase, TDT, Terminal transferase |
2 | D, U | 5'-D(*AP*AP*AP*AP*AP*C)-3' | polymer | 6 | 1810.3 | 2 | |||
3 | T | 5'-D(*TP*TP*TP*TP*TP*GP*A)-3' | polymer | 7 | 2118.4 | 1 | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | A | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE | non-polymer | 451.2 | 1 | Chemie (DCT) | |||
7 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 132 - 482 (UniProt: P09838)
A: 483 - 510 (UniProt: P09838)
PDB | External Database | Details |
---|---|---|
Met 111 | - | expression tag |
Gly 112 | - | expression tag |
Ser 113 | - | expression tag |
Ser 114 | - | expression tag |
His 115 | - | expression tag |
His 116 | - | expression tag |
His 117 | - | expression tag |
His 118 | - | expression tag |
His 119 | - | expression tag |
His 120 | - | expression tag |
Ser 121 | - | expression tag |
Ser 122 | - | expression tag |
Gly 123 | - | expression tag |
Leu 124 | - | expression tag |
Val 125 | - | expression tag |
Pro 126 | - | expression tag |
Arg 127 | - | expression tag |
Gly 128 | - | expression tag |
Ser 129 | - | expression tag |
His 130 | - | expression tag |
Met 131 | - | expression tag |
Ala 401 | Phe 401 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 51366.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 522.8 | |
All* | Total formula weight | 51889.6 |