4QWN

Histone demethylase KDM2A-H3K36ME1-alpha-KG complex structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Lysine-specific demethylase 2A	polymer	329	39031.3	2	UniProt (F6YRW4) Pfam (PF17811) UniProt (by SIFTS) (P59997)	Mus musculus (mouse)	F-box and leucine-rich repeat protein 11, F-box/LRR-repeat protein 11, JmjC domain-containing histone demethylation protein 1A, [Histone-H3]-lysine-36 demethylase 1A
2	B, D (B, D)	Lysine-specific demethylase 2A	polymer	68	7534.8	2	UniProt (F6YRW4) UniProt (by SIFTS) (P59997)	Mus musculus (mouse)	F-box and leucine-rich repeat protein 11, F-box/LRR-repeat protein 11, JmjC domain-containing histone demethylation protein 1A, [Histone-H3]-lysine-36 demethylase 1A
3	E, F (E, F)	Histone H3.2	polymer	15	1652.9	2	UniProt (P84228)	Mus musculus
4	G, I (A, C)	2-OXOGLUTARIC ACID	non-polymer		146.1	2	Chemie (AKG)
5	H, J (A, C)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
6	K, L, M, N, O (A, B, C, D, F)	water	water		18.0	195	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	96438.0
Non-Polymers*	Number of molecules	4
	Total formula weight	409.6
All*	Total formula weight	96847.6

*Water molecules are not included.