4QUJ
Caspase-3 T140GV266H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Caspase-3 | polymer | 278 | 31785.0 | 1 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12 |
| 2 | F | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR | polymer | 6 | 534.9 | 1 | BIRD (PRD_000238) | ||
| 3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | A | AZIDE ION | non-polymer | 42.0 | 2 | Chemie (AZI) | |||
| 5 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 1 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Gly 140 | Thr 140 | ENGINEERED MUTATION |
| His 266 | Val 266 | ENGINEERED MUTATION |
| His 278 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32320.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 225.2 | |
| All* | Total formula weight | 32545.2 |
