4QUI
Caspase-3 F128AV266H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Caspase-3 | polymer | 278 | 31728.0 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12 |
| 2 | C, D (D, C) | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | ||
| 3 | E, H (A, C) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 2 | Chemie (DTT) | |||
| 4 | F, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I, J, K, L (A, B, D, C) | water | water | 18.0 | 463 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 128 | Phe 128 | ENGINEERED MUTATION |
| His 266 | Val 266 | ENGINEERED MUTATION |
| Leu 278 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 64525.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 379.4 | |
| All* | Total formula weight | 64905.3 |
