4QUH
Caspase-3 T140G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Caspase-3 | polymer | 277 | 31607.9 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12 |
| 2 | C (D) | short peptde | polymer | 5 | 519.5 | 1 | |||
| 3 | D, E (I, J) | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | ||
| 4 | F, I (A, C) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 2 | Chemie (MRD) | |||
| 5 | G, H, J, K (A, C) | AZIDE ION | non-polymer | 42.0 | 4 | Chemie (AZI) | |||
| 6 | L (C) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 7 | M, N, O, P, Q (A, C, D, I, J) | water | water | 18.0 | 421 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Gly 140 | Thr 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 64805.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 558.7 | |
| All* | Total formula weight | 65363.8 |
