4QU9
Caspase-3 F128A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-3 | polymer | 279 | 31827.1 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12 |
| 2 | B (E) | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR | polymer | 6 | 534.9 | 1 | BIRD (PRD_000238) | ||
| 3 | C, D, E, F, G... (A) | AZIDE ION | non-polymer | 42.0 | 6 | Chemie (AZI) | |||
| 4 | I, J (A, E) | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
A: 1 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 128 | Phe 128 | engineered mutation |
| Leu 278 | - | expression tag |
| His 279 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32362.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 252.1 | |
| All* | Total formula weight | 32614.2 |
