4QU0
Caspase-3 Y195AV266H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-3 | polymer | 278 | 31737.0 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12 |
| 2 | B (E) | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR | polymer | 6 | 534.9 | 1 | BIRD (PRD_000238) | ||
| 3 | C (A) | AZIDE ION | non-polymer | 42.0 | 1 | Chemie (AZI) | |||
| 4 | D, E (A, E) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A: 1 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Tyr 195 | engineered mutation |
| His 266 | Val 266 | engineered mutation |
| His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32271.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 42.0 | |
| All* | Total formula weight | 32314.0 |
