4QTY
Caspase-3 E190A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-3 | polymer | 250 | 28612.6 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12 |
| 2 | B (F) | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR | polymer | 6 | 534.9 | 1 | BIRD (PRD_000238) | ||
| 3 | C (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | D (A) | AZIDE ION | non-polymer | 42.0 | 1 | Chemie (AZI) | |||
| 5 | E, F (A, F) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence modifications
A: 29 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 190 | Glu 190 | engineered mutation |
| His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29147.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 65.0 | |
| All* | Total formula weight | 29212.6 |
