4QT3
Crystal structure resolution of Plasmodium falciparum FK506 binding domain (FKBP35) in complex with Rapamycin at 1.4A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FK506-binding protein (FKBP)-type peptidyl-propyl isomerase | polymer | 134 | 15215.1 | 1 | UniProt (Q8I4V8) Pfam (PF00254) | Plasmodium falciparum 3D7 | |
| 2 | B (A) | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL | non-polymer | 154.3 | 1 | Chemie (DTV) | |||
| 3 | C (A) | RAPAMYCIN IMMUNOSUPPRESSANT DRUG | non-polymer | 914.2 | 1 | Chemie (RAP) | |||
| 4 | D (A) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A: 5 - 127 (UniProt: Q8I4V8)
| PDB | External Database | Details |
|---|---|---|
| Leu 128 | - | expression tag |
| Glu 129 | - | expression tag |
| Glu 130 | - | expression tag |
| Thr 131 | - | expression tag |
| Ser 132 | - | expression tag |
| His 133 | - | expression tag |
| His 134 | - | expression tag |
| His 135 | - | expression tag |
| His 136 | - | expression tag |
| His 137 | - | expression tag |
| His 138 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15215.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1068.4 | |
| All* | Total formula weight | 16283.5 |
