4QQD
Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | E3 ubiquitin-protein ligase UHRF1 | polymer | 161 | 18824.0 | 2 | UniProt (Q96T88) Pfam (PF12148) In PDB | Homo sapiens (human) | Inverted CCAAT box-binding protein of 90 kDa, Nuclear protein 95, Nuclear zinc finger protein Np95, HuNp95, hNp95, RING finger protein 106, Transcription factor ICBP90, Ubiquitin-like PHD and RING finger domain-containing protein 1, hUHRF1, Ubiquitin-like-containing PHD and RING finger domains protein 1 |
| 2 | A, B | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine | non-polymer | 188.3 | 3 | Chemie (36X) | |||
| 3 | A, B | UNKNOWN ATOM OR ION | non-polymer | 5 | Chemie (UNX) | ||||
| 4 | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A, B: 126 - 285 (UniProt: Q96T88)
| PDB | External Database | Details |
|---|---|---|
| Gly 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37647.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 564.8 | |
| All* | Total formula weight | 38212.7 |
